Question: Make picturebox = mouse

Hello,

I am working on a very simple game, but cannot detect collisions with pictureboxes.
I have googled how to make pictureboxes collide, but, I can't find anything.
My thought was, "Is it possible to trick a program into thinking a picturebox is a
mouse?"

I don't think it's possible, but, is their a way for a picturebox to detect another
picturebox when they touch?

Thanks,
Zues90